Yu Galaxy Research
Investment Thesis & Core Philosophy
Yu Galaxy is a mission-driven venture capital firm founded by P.R. Yu, a distinguished scientist-turned-entrepreneur-turned-investor with $500M+ in assets under management. The firm operates as a solo-GP fund, meaning P.R. Yu is the sole decision-maker, enabling unmatched speed and conviction-based investing. The core investment thesis centers on backing visionary founders solving humanity's toughest problems—particularly in healthcare, AI, robotics, defense, and automation—where innovation saves lives, advances science, and protects the planet.
P.R. Yu's philosophy is distinctive: "Impact and profit are inseparable." The firm explicitly measures success in both lives saved and financial returns. Unlike traditional VCs that slow founders down, Yu Galaxy moves with exceptional agility. P.R. has a proven track record of funding within days (not months), saving rounds at critical deadlines, and backing companies when others overlook them. Portfolio companies have achieved 30x+ valuation increases within five years, validating the thesis that measurable impact and outsized returns align.
The investment approach is rooted in five core values: passion, service, education and growth, equity, and community. These principles guide conviction-based investing and long-term founder partnerships.
Investment Stage & Check Size
Yu Galaxy invests at the earliest stages, with primary focus on Pre-Seed and Seed rounds. The firm is explicit about partnering "early with founders—often before they recognize themselves as visionaries." Check sizes appear flexible, ranging from early-stage seed investments to follow-ons, with emphasis on funding quality founders rather than rigid check minimums. Decision timelines are rapid: P.R. Yu personally evaluates all pitches and can move deal from pitch to funding in days, not months.
Recent Activity & Fund Status
Yu Galaxy recently closed a $90M funding round in 2024-2025, bringing total AUM to $500M+, positioning the firm as one of America's largest solo-GP-led funds. The firm is actively deploying capital with strong momentum across healthcare and deeptech sectors. Recent portfolio company exits and funding rounds demonstrate active deal flow and successful follow-on investing:
- Leo Cancer Care (proton radiotherapy, hospitals including Stanford & McLaren adopting devices)
- Inquis Medical (Series B $40M, thrombectomy systems)
- Capstan Medical (Series round with Eclipse, cardiac robotics)
- Aqtual (Series A $16M, precision medicine)
- Multiple portfolio companies scaling to 30x+ valuations
Portfolio & Sector Focus
Yu Galaxy's public portfolio ("Stars") includes 15+ companies across interconnected deeptech and healthtech sectors:
Healthcare & Medical Devices:
- Leo Cancer Care (upright radiotherapy for cancer treatment)
- Inquis Medical (thrombectomy systems for vascular disease)
- Capstan Medical (cardiac robotics for structural heart disease)
- Aqtual (precision medicine, personalized treatments)
- Celebrace (AI-driven orthodontics)
AI & Data Intelligence:
- InsightFinder (AI engine for infrastructure/security/data problems)
- Divinia.ai (AI for search and e-commerce)
- AuditoryAI (AI-enabled hearing personalization)
Advanced Materials & Hardware:
- GruEnergy (silicon-based lithium-ion battery anodes)
- Double Helix Optics (nanoscale imaging with rotating PSF)
- Airity (high-voltage power supply units, 10x smaller/50x more power-dense)
- Elve (millimeter wave amplifiers for wireless internet)
- RaySecur (millimeter wave imaging for mail security)
Robotics & Automation:
- WiBotic (wireless charging and fleet management for robots/drones)
Fintech & Payments:
- Zact (bank-grade spend management platform)
Remote Monitoring:
- Turnkey remote patient monitoring platform
Portfolio characteristics show heavy concentration in deeptech (hardware, materials science, AI), healthtech (medical devices, precision medicine), and automation—sectors with clear social impact and high technical barriers to entry.
Team & Decision-Making
P.R. Yu, Founder & Managing Partner:
- Peking University (0.01% acceptance rate)
- Ph.D. in Physical Chemistry, University of Colorado Boulder (full scholarship)
- Former scientist developing solar energy technologies
- Founded his own company to commercialize innovations for social impact
- 100+ founder investments with multiple exits and IPOs
- Portfolio exits include companies saving lives in 50+ countries
- Philanthropic orientation: donates 100% of speaking fees to charities
- Serves as Advisor for Research and Innovation to CU Boulder
Vahid Saadat, Venture Partner:
- 25+ years medical device development and commercialization experience
- CEO of Voyage Medical (backed by Kleiner Perkins, Three Arch, RWI, Abbott Ventures)
- Founded Arrinex (acquired by Stryker)
- Currently runs Inquis Medical
- 200+ patents across medical specialties
Mark Zhu, Venture Partner:
- 35+ deeptech investments since 2008
- Digital transformation and sustainability focus
- Multiple exits: A123 (IPO), QD Vision (Samsung), Device42, SeeClickFix (CivicPlus), LiveOak (DocuSign), MoQuality (Snap)
Solo-GP Model: Unlike traditional partnerships, P.R. Yu serves as sole decision-maker, enabling rapid decision-making and conviction-based investing without committee consensus. Venture partners provide operational and sector expertise but P.R. maintains final authority.
Founder Preferences & Investment Criteria
Yu Galaxy backs founders with:
- Visionary thinking: Founders with bold ideas addressing humanity's hardest problems
- Big hearts over big egos: Emphasis on humble, world-changing founders
- Technical depth: Scientific/engineering founders with domain expertise (scientist → entrepreneur trajectory valued)
- Problem intimacy: Founders deeply committed to specific global challenges
- Execution capability: Ability to move fast and implement with conviction
- Mission alignment: Founders whose goals align with impact thesis
P.R. Yu has demonstrated willingness to back founders at unconventional stages—sometimes before they fully recognize their own visionary potential.
Geographic Focus & Decision Timeline
Geographic Scope: Primarily US-focused with global ambitions (portfolio companies operating in 50+ countries). No explicit geographic restrictions stated.
Decision Timeline: Days to weeks. P.R. Yu personally evaluates all pitches and can fund within days of conviction. This speed advantage is a key differentiator—the firm has historically stepped in at critical round deadlines where other VCs were slow.
Typical Involvement: Advisor-level engagement with founder support and network leverage. P.R. Yu personally mentors founders and provides strategic guidance.
Key Differentiators
- Solo-GP Model: Speed and conviction-based decision-making without committee consensus
- Proven Track Record: 100+ founder investments, multiple exits and IPOs, 30x+ portfolio valuations in 5 years
- Mission-Driven: Explicit focus on impact + returns, not returns alone
- Deep Domain Expertise: P.R. Yu's scientist background enables sophisticated evaluation of deeptech/healthtech
- Rapid Funding: Days-to-weeks decision timelines vs. industry standard months
- Founder-Centric: Values big hearts over big egos; willing to back founders others overlook
- Global Impact: Portfolio companies operating across 50+ countries with social/environmental benefit
- Significant Capital: $500M+ AUM positions as major solo-GP player
Investment Profile & Preferences
Lead Tendency: Leads early rounds. The firm's solo-GP structure and rapid decision-making position it well to lead seed and pre-seed rounds where conviction matters most.
Warm Intro Required: Not explicitly required, though P.R. Yu likely receives exceptional deal flow through network.
Co-investors: Portfolio companies have attracted co-investors from ecosystem partners; Capstan Medical round led by Eclipse demonstrates willingness to collaborate.
Board Involvement: Not stated explicitly, but "advisor-level engagement" suggests advisory role without board seat.
Notable Characteristics
- Exceptional LP Network: $500M+ AUM demonstrates strong LP confidence
- Long Conviction Window: Willing to back founders and ideas when consensus hasn't formed
- Geographic Impact: Portfolio creates impact globally (50+ countries)
- Repeat Founder Backing: P.R. Yu has backed 100+ founders—indicating consistent deal flow and selection expertise
- Venture Partner Network: Experienced deeptech operators (Vahid's medical device expertise, Mark's 35+ deeptech investments) provide operational depth beyond P.R.'s involvement
- Philanthropic Culture: P.R. Yu's 100% speaking fee donation and support for K-12/university programs reflect impact-first culture
Fund Structure
Yu Galaxy operates as a single fund structure with P.R. Yu as sole decision-maker, supported by two venture partners providing sector-specific expertise and operational support. No mention of separate vehicles or syndicate structures.
Investment Philosophy Summary
Yu Galaxy represents a distinctive approach to venture capital: conviction-based solo-GP investing focused on deeptech and healthtech founders solving humanity's toughest problems. The firm explicitly rejects the notion that impact and profit are in conflict, instead backing this thesis with portfolio performance (30x+ valuations) and measurable global impact (companies operating in 50+ countries). P.R. Yu's unique background (scientist → entrepreneur → investor) enables sophisticated evaluation of technical founders and deeptech problems. The combination of rapid decision-making, founder-centric values, and proven performance creates a compelling differentiation in the VC landscape.